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Dopamine agonists


By Serge Kreutz (2004)

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Dopamine agonists have been around for many decades, and their pro-libido effect has been reported. Apart from Dostinex, the assortment of dopamine agonists includes bromocriptine, pergolide, pramipexole, lisuride, apomorphine, and a few more.

Actually, apomorphine (brand name: Uprima) was sold in Europe as a medication for erectile dysfunction. But it's wrong marketing. Dopamine agonists don't work for erections like phosphodiesterase inhibitors. They work on libido, at least for some people who use them.

Uprima typically is a disappointment for men whose problems are primarily vascular. I assume that Uprima is sold as a medication for erectile dysfunction mainly because erectile dysfunction meanwhile is an accepted medical condition, while low libido is not.

I have tried dopamine agonists for sexual enhancement for several years. And not only dopamine agonists.

To summarize my observation: while sildenafil citrate and yohimbine work on erections, and while elevating testosterone levels only is of a pro-sexual nature if it is done with tongkat ali extract, dopamine agonists can enhance sexual excitement, though not reliably.

Because dopamine agonists suppress the hormone prolactin, which in turn suppresses testosterone, dopamine agonists can, in people with elevated prolactin levels, function in the same way as a testosterone replacement therapy would. This most happens in patients with pituitary cancer, which typically expresses itself in strongly elevated prolactin levels. Those afflicted by the disease have very low testosterone levels. Thus, for them, Dostinex and other dopaminergic agents work as hormonal therapy. The hormonal effects of Dostinex are less pronounced, or totally absent, in healthy subjects.

On the other hand, tongkat ali not only supports sexual excitement; it also tends to enhance orgasm and make for a stronger ejaculations. Tongkat ali can account for an additional half meter in ejaculatory range (and ejaculations on tongkat ali can feel like pellets, not fluid, moving through the urethra). Orgasms in general will be much more overwhelming.

In comparison to tongkat ali, dopamine agonists have their downsides. All the older ones can cause nausea. I myself cannot take L-dopa or lisuride. Nausea on these drugs is so severe that I want to see a nurse, rather than a girl, and only for medical purposes.


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Copyright Serge Kreutz